Table 1 of Vergara, Mol Vis 2009; 15:1000-1013.

Table 1. Summary of the results obtained with the MAPK inhibition experiments.


Treatment		 Regeneration
n
Significant
p-value
None Reduced Normal
FGF+control 0 3 13 16

FGF+U0126 100 mM 0 5 5 10 yes <0.01
FGF+U0126 1 mM 5 0 0 5 yes < 0.001

A chi square test was used to assess statistical significance when comparing eyes treated with FGF-2 plus inhibitor (U0126) to control eyes (FGF-2 plus control bead). Treatment with the MEK inhibitor significantly reduced retinal regeneration in this system.

Vergara, Mol Vis 2009; 15:1000-1013. http://www.molvis.org/molvis/v15/a105

©2009 Molecular Vision http://www.molvis.org/molvis/

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