Figure 1. Autosomal recessive cataract family is linked to CRYB. A: CNAG analysis shows an area of homozygosity that is shared between affected family members on chromosome 11 as indicated by the pink bars. Microsatellite markers flanking the homozygosity region are shown. B: The two-generation pedigree shows the affected and unaffected members in shaded and open circles/boxes, respectively. Roman numbers denote generations, and Arabic numbers denote individuals within generations. C: Linkage analysis reveals the highest LOD score on chromosome 11 as the red arrow indicates.