Table 1 of Gregory-Evans, Mol Vis 2009; 15:962-973.

Table 1. Side effects associated with intravitreal injection into TgN S334ter rat eyes.



Treatment

Endophthalmitis

Cataract		 Total
retinal
detachment		 Minor
traction
detachment
GDNF-secreting mES cells (n=34) 0 2 0 2
Unmodified mES cells (n=15) 0 3 2 1
PBS sham injections (n=19) 1 0 0 0

Data from 68 treated eyes. These data show that complications were seen in rats regardless of the type of intravitreal injection but that retinal side effects were seen only in rats treated with unmodified or GDNF-secreting mES cells. Abbreviations: glial-derived neurotrophic factor (GDNF), mouse embryonic stem (mES), phosphate buffer solution (PBS).

Gregory-Evans, Mol Vis 2009; 15:962-973. http://www.molvis.org/molvis/v15/a101

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