Figure 2. Eyes of Dca rats. A:
Whole eyeball preparations from mutant homozygotes (Dca/Dca),
heterozygotes (+/Dca), and wild type controls (+/+) are shown.
Heterozygotes show well developed nuclear cataract while the mutant
homozygotes display microphthalmia. B: Eye weight is shown for
each (mutant homozygotes, heterozygotes, and wild type controls). The
data represent means±SEM of the average weight of the left and right
eye. The differences are significant (ANOVA F=290.7, p=0, post-hoc
comparison with Spjotvoll-Stoline honest significant difference test
yielded p=0.00011 among all pairs). The Dca allele decreases
eye size in an approximately additive manner. Dca/Dca
homozygotes, n=52, 0.0538±0.0012 g; +/Dca homozygotes, n=51,
0.0781±0.0012 g; WT=+/+ (wild-type) controls, n=13, 0.1128±0.0019 g.