Figure 1. Segregation of primary open-angle glaucoma in a large family from Taxiarchis (Taxi 2). Note that A23 is homozygous for the Thr377Met mutation. A filled-in symbol indicates that the person has been diagnosed with POAG. The number under the symbol indicates the specific code given to the family member who participated in the study. The MYOC genotype is denoted below the code. The arrow indicates the proband for the pedigree.