Figure 1. Cataract pedigree and haplotype analysis. Pedigree and haplotype analysis of the cataract family shows the segregation of three microsatellite markers on chromosome 22q11.2–12.1, which is listed in descending order from the centromere. Squares and circles symbolize males and females, respectively. The clear and shaded symbols denote unaffected and affected individuals, respectively. The proband is marked with an arrow.