Figure 1. Pedigree and haplotype analysis. Shown is a pedigree of a consanguineous Israeli Muslim Arab family segregating early-onset autosomal recessive retinitis pigmentosa (family TB13). Haplotype analysis performed on this family demonstrated co-segregation of a haplotype of three polymorphic marker alleles, linked to TULP1 on chromosome 6p21.31, with autosomal recessive retinitis pigmentosa in this family. The mutation-bearing haplotype is marked by a box. Males are represented by squares, females are represented by circles. Affected individuals are marked by black shadings.