Figure 4. Photoreceptor degeneration is not detected following intracameral inoculation. Inoculation of mice with allosplenocytes intracamerally was compared to positive control (positive c.) and negative control (negative c.) mice. Outer nuclear layer (ONL) thickness was measured histologically over time to identify potential photoreceptor degeneration (n of 7 per micrograph). Representative micrographs of neuroretinal cross-sections include the ganglion cell layer (RGC), outer plexiform layer (OPL), and outer nuclear layer (ONL). Micrographs demonstrate a loss in ONL thickness in positive control mice only. A: These data are summarized (B) in the adjacent bar graph. Asterisk (*) indicates p value ≤ 0.02, as calculated by ANOVA.