Molecular Vision: Bayat, Mol Vis 2008; 14:508-517. Table 2

Table 2. Phenotypic features of Iranian JOAG patients.

Pedigree	F/S	Inheritance	Age at diagnosis	C/D ratio R/L	IOP max (mmHg) R/L	Trabeculotomy	Age of onset range	MYOC Haplotype
JG104#	S		14 years	0.3/0.6	30/34	1x		H1, H2*
JG120	S		40 years	0.6/0.6	40/40	1x		H1, H1*
JG123#	S		17 years	0.3/0.4	22/29	1x		H1, H1*
JG127	S		32 years	0.3/0.3	30/30	1x		H1, H1*
JG130#	S		14 years	0.3/0.5	20/30	1x		H1, H2*
JG113	F	AD	40 years	0.5/0.9		multiple	5–40 years	H2, H3
JG117	F	AD	17 years	0.9/0.4	34/34	1x	17–22 years	H2, H3
JG118	F	AD	17 years		33/33	2x	Birth-60 years	H1, H1*
JG121	F	AD	27 years	0.3/0.4	33/34	1x	27–58 years	H1, H2*
JG101	F	AR	16 years	0.6/0.3	33/34	2x	Birth-22 years	H1, H2*
JG103##	F	AR	19 years	0.5/0.5	/33	1x	19–20 years	H1, H3 or H2, H4
JG105	F	AR	24 years		normal/33	1x	24–29 years	H2, H2*
JG107	F	AR	10 years	0.3/0.3		1x		H2, H2*
JG111	F	AR	32 years		high/high	2x	32–36 years	H1, H2*
JG114##	F	AR	18 years	0.3/0.3		1x	5–30 years	H3, H3*
JG129##	F	AR	L: birth R: 12 years	0.6/0.3	30/		Birth-12 years	H1, H1*
JG131	F	AR	L: 12 years R: birth	0.5/0.3	28/24	1x	Birth-45 years	H1, H4
JG100##	F	?	10 years	0.5/0.6	35/35	3x	Birth-12 years	H1, H2*
JG102#	F	?	19 years	0.5/0.3	33/34	1x	7–20 years	H2, H2*
JG110	F	?	14 years	0.5/0.3		2x	14–35 years	H2, H2*
JG112	F	?	30 years	0.5/0.5		1x	5–60 years	H1, H1*
JG122	F	?	25 years	0.3/0.3		1x		H1, H4
JG134	F	?	30 years	0.4/0.9	34/34			H1, H4

Unknown clinical features are left blank. For familial cases, features of the proband of the families are presented. The meaning of each symbol and abbreviation is given in the following: F/S indicated the familial/sporadic status of patients: F, familial; S, sporadic; AD: autosomal dominant; AR: autosoamal recessive; ?: unknown mode of inheritance; R: right eye; L: left eye; Age of onset range is the range of age of onset in other affected family members; MYOC haplotypes are defined by SNPs at positions c.-83, c.227, and IVS2+35 in the same order. H1: -GGG-, H2: -GGA-, H3: -AAA-, H4: -AAG-; The sharp (hash mark) indicates patients in whom MYOC disease-associated variations were found; the double sharp indicates patients in whom CYP1B1 disease-associated variations were found; the asterisk indicates that the haplotypes of these patients were unambiguous. Those of the remaining patients were predicted.