Table 3 of Abu-Amero, Mol Vis 2008; 14:425-430.

Table 3. Glutathione S-transferase genotypes and the risk of developing primary open-angle glaucoma.

GST genotypes Controls (n=120) POAG patients (n=49) Odds ratio 95% Confidence interval p-Value
T1M1 102 (85%) 18(36.7%) Reference - -
T0M0 3 (2.5%) 3 (6.2%) 5.67 0.83 – 39.2 0.06
T1M0 10 (8.3%) 18 (36.7%) 10.2 3.72 – 28.6 0.00001
T0M1 5 (4.2%) 10 (20.4%) 11.3 3.07 – 44.0 0.00001

The frequency of the T1M0 and T0M1 genotypes was significantly greater in POAG patients than controls (p=0.00001), while the frequency of the T0M0 null genotype which was not significant (p=0.06). After Bonferroni correction, p-value < 0.0167 was considered statistically significant.

Abu-Amero, Mol Vis 2008; 14:425-430. http://www.molvis.org/molvis/v14/a52

©2008 Molecular Vision http://www.molvis.org/molvis/

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