Figure 2. VEGF concentration increased in the 50/10 oxygen-induced retinopathy model compared to room air. A: Vascular endothelial growth factor (VEGF). VEGF concentration was increased in the 50/10 oxygen-induced retinopathy (OIR) model compared to RA at all time points (overall ANOVA p<0.001; post-hoc Student’s t-tests * p<0.001). In 50/10 OIR model, VEGF concentration at p14 was greater than at p12 or 18 (ANOVA p<0.001; posthoc Student’s t-tests, * p<0.001; n=6 for each time point). B: VEGF concentration was measured by ELISA in the retina (204.5±12.4 pg/mg) and vitreous (15.7±4.3 pg/mg) of p18 OIR-raised rat pups (n=12 for 50/10 OIR and RA).