Figure 1. Effect of retinal detachment on vitreous cyclic guanosine monophosphate (cGMP)(pmol/ml) levels. A retinal detachment was induced in the right eyes of six pigs. Fourteen days later the eyes were enucleated and vitreous from detached and non-detached eyes was collected and analyzed for cGMP content with an immunoassay. The figure shows the individual cyclic GMP levels in the eyes with a detached or non-detached retina from each pig. It is clear that the vitreous cGMP level in the eyes with a detached retina is lower that that from the control eyes.