Figure 3. Effect of St. John’s Wort and hypericin on physiologic vascularization in the retina. A-C: Shown are representative images of mouse retinas immunostained with isolectin B4 after treatment with 15 mg/kg/day St. John’s Wort (SJW; n=18), 45 µg/kg/day hypericin (n=16), or vehicle (n=18) from P3 to P7. Magnification is X 5. D: Measurement of length of vasculature from the optic disc to the edge of the vascular front. Data are presented as mean ± SEM. N.S. means the data was not statistically significant.