Table 5 of Hou, Mol Vis 2008; 14:2597-2603. Table 5 of Hou, Mol Vis 2008; 14:2597-2603.
Table 5. Stratification analysis for HLA-DRw53 and SUMO4 polymorphisms and the comparison of frequencies of SUMO4 allele and genotype in HLA-DRw53+ patients versus HLA-DRw53+ controls and HLA-DRw53- patients versus HLA-DRw53- controls.
SNPs |
Genotype allele |
HLA-DRw53+ Patients n=203 (%) |
HLA-DRw53+ Controls n=193 (%) |
p value |
pca value |
HLA-DRw53- Patients n=28 (%) |
HLA-DRw53- Controls n=109 (%) |
p value |
pca value |
|---|---|---|---|---|---|---|---|---|---|
| −847 G→A | GG | 13 (6.5) | 20 (10.5) | 0.368 | NSb | 3 (11.1) | 10 (9.4) | 0.200 | NS |
| AG | 91 (45.7) | 83 (43.7) | 13 (48.1) | 33 (31.1) | |||||
| AA | 95 (47.7) | 87 (45.8) | 11 (40.7) | 63 (59.4) | |||||
| G | 117 (29.4) | 123 (32.4) | 0.370 | NS | 19 (35.2) | 53 (25.0) | 0.133 | NS | |
| A | 281 (70.6) | 257 (67.6) | 35 (64.8) | 159 (75.0) | |||||
| −504 A→G | AA | 43 (21.7) | 43 (22.6) | 0.742 | NS | 11 (40.8) | 23 (21.5) | 0.114 | NS |
| AG | 97 (49.0) | 98 (51.6) | 10 (37.0) | 48 (44.9) | |||||
| GG | 58 (29.3) | 49 (25.8) | 6 (22.2) | 36 (33.6) | |||||
| A | 183 (46.2) | 184 (48.4) | 0.538 | NS | 32 (59.3) | 94 (43.9) | 0.044 | NS | |
| G | 213 (53.8) | 196 (51.6) | 22 (40.7) | 120 (56.1) | |||||
| +163 A→G | AA | 96 (47.5) | 83 (43.0) | 0.590 | NS | 11 (39.3) | 62 (56.9) | 0.216 | NS |
| AG | 93 (46.0) | 94 (48.7) | 14 (50.0) | 36 (33.0) | |||||
| GG | 13 (6.4) | 16 (8.3) | 3 (10.7) | 11 (10.1) | |||||
| A | 285 (70.5) | 260 (67.4) | 0.333 | NS | 36 (64.3) | 160 (73.4) | 0.178 | NS | |
| G | 119 (29.5) | 126 (32.6) | 20 (35.7) | 58 (26.6) | |||||
| +438 C→T | CC | 95 (47.3) | 82 (42.5) | 0.035 | NS | 12 (42.9) | 53 (48.6) | 0.613 | NS |
| CT | 95 (47.3) | 86 (44.6) | 12 (42.9) | 36 (33.0) | |||||
| TT | 11 (5.5) | 25 (13.0) | 4 (14.3) | 20 (18.3) | |||||
| C | 285 (70.9) | 250 (64.8) | 0.065 | NS | 36 (64.3) | 142 (65.1) | 0.905 | NS | |
| T | 117 (29.1) | 136 (35.2) | 20 (35.7) | 76 (34.9) |