Table 4 of Hou, Mol Vis 2008; 14:2597-2603. Table 4 of Hou, Mol Vis 2008; 14:2597-2603.
Table 4. Stratification analysis for HLA-DR4 and SUMO4 polymorphisms and the comparison of frequencies of SUMO4 allele and genotype in HLA-DR4+ patients versus HLA-DR4+ controls and HLA-DR4- patients versus HLA-DR4- controls.
SNPs |
Genotype allele |
HLA-DR4+ Patients n=179 (%) |
HLA-DR4+ Controls n=59 (%) |
p value |
pca value |
HLA-DR4- Patients n=52 (%) |
HLA-DR4- Controls n=243 (%) |
p value |
pca value |
|---|---|---|---|---|---|---|---|---|---|
| −847 G→A | GG | 12 (6.8) | 10 (17.2) | 0.041 | NSb | 4 (8.0) | 20(8.4) | 0.757 | NS |
| AG | 81 (46.0) | 20 (34.5) | 23 (46.0) | 96 (40.3) | |||||
| AA | 83 (47.2) | 28 (48.3) | 23 (46.0) | 122 (51.3) | |||||
| G | 105 (29.8) | 40 (34.5) | 0.347 | NS | 31 (31.0) | 136 (28.6) | 0.627 | NS | |
| A | 247 (70.2) | 76 (65.5) | 69 (69.0) | 340 (71.4) | |||||
| −504 A→G | AA | 40 (22.9) | 11 (19.0) | 0.656 | NS | 14 (28.0) | 55 (23.0) | 0.696 | NS |
| AG | 85 (48.6) | 27 (46.6) | 22 (44.0) | 119 (49.8) | |||||
| GG | 50 (28.6) | 20 (34.5) | 14 (28.0) | 65 (27.2) | |||||
| A | 165 (47.1) | 49 (42.2) | 0.359 | NS | 50 (50.0) | 249 (52.1) | 0.703 | NS | |
| G | 185 (52.9) | 67 (57.8) | 50 (50.0) | 229 (47.9) | |||||
| +163 A→G | AA | 84 (46.9) | 29 (49.2) | 0.820 | NS | 23 (45.1) | 116 (47.7) | 0.872 | NS |
| AG | 83 (46.4) | 25 (42.4) | 24 (47.1) | 105 (43.2) | |||||
| GG | 12 (6.7) | 5 (8.5) | 4 (7.8) | 22 (9.1) | |||||
| A | 251 (70.1) | 83 (70.3) | 0.963 | NS | 70 (68.6) | 337 (69.3) | 0.887 | NS | |
| G | 107 (29.9) | 35 (29.7) | 32 (31.4) | 149 (30.7) | |||||
| +438 C→T | CC | 82 (46.3) | 29 (49.2) | 0.089 | NS | 25 (48.1) | 106 (43.6) | 0.562 | NS |
| CT | 85 (48.0) | 22 (37.3) | 22 (42.3) | 100 (41.2) | |||||
| TT | 10 (5.6) | 8 (13.6) | 5 (9.6) | 37 (15.2) | |||||
| C | 249 (70.3) | 80 (67.8) | 0.603 | NS | 72 (69.2) | 312 (64.2) | 0.328 | NS | |
| T | 105 (29.7) | 38 (32.2) | 32 (30.8) | 174 (35.8) |