Figure 4. mPins mRNA localization in
nonretinal structures by in situ hybridization. mPins mRNA
localization in the adult cornea (A and B), the ciliary
body (C), the iris (D) at 2 months (2M), and in the lens
at P3 (E), P9 (F) and at 2M (G). In the cornea, mPins
mRNA is observed in the epithelium (CEp), stroma (CS), and endothelium
(CEn; A). A high magnification of A also shows mPins
mRNA to be present in the stromal keratocytes (ke; B).
Significant labeling was also detected in the nonpigmented ciliary
epithelial cells (NPCE) of the ciliary body (C). No significant
labeling is observed in the pigmented ciliary epithelial cells (PCE; C),
and weak mPins mRNA labeling is detected in the iris (Ir; D).
In the lens, mPins mRNA is observed in the epithelium (Le),
transitional zone (Tz), and lens fibers (Lf) from early postnatal
stages to adulthood (D-G).
