Table 3 of Fan, Mol Vis 2008; 14:2484-2491. Table 3 of Fan, Mol Vis 2008; 14:2484-2491.
Table 3. Single-SNP association of homocysteine genes with PXFS after controlling for the effects of age and 3 LOXL1 SNPs.
| Gene | SNP | Minor allele | p value* | OR (95% CI)* |
|---|---|---|---|---|
| MTHFR | rs1801131 | C | 0.95 | 0.98 (0.49, 1.96) |
| MTHFR | rs1801133 | T | 0.55 | 0.79 (0.37, 1.70) |
| MTHFR | rs17037396 | T | 0.81 | 0.89 (0.33, 2.40) |
| MTR | rs12096955 | T | 0.23 | 1.43 (0.80, 2.54) |
| MTR | rs2229274 | A | 0.55 | 0.52 (0.06, 4.41) |
| MTR | rs1805087 | G | 0.69 | 0.90 (0.52, 1.55) |
| MTRR | rs326122 | G | 0.95 | 1.02 (0.50, 2.07) |
| MTRR | rs1532268 | T | 0.82 | 1.09 (0.50, 2.38) |
| MTRR | rs161870 | A | 0.46 | 0.74 (0.33, 1.65) |
| MTRR | rs162036 | A | 0.91 | 0.96 (0.49, 1.90) |
| MTHFD1 | rs8006686 | C | 0.21 | 1.62 (0.76, 3.45) |
| MTHFD1 | rs2236225 | T | 0.77 | 0.93 (0.59, 1.47) |
| MTHFD1 | rs11627387 | G | 0.24 | 0.68 (0.36, 1.29) |
| CBS | rs2124459 | C | 0.71 | 1.13 (0.61, 2.10) |
| CBS | rs1801181 | T | 0.49 | 1.18 (0.74, 1.89) |
| CBS | rs5742905 | C | 0.12 | 2.07 (0.84, 5.14) |
| CBS | rs234715 | G | 0.57 | 0.80 (0.36, 1.74) |