Table 5 of Gong, Mol Vis 2008; 14:2381-2389.

Table 5. Haplotype analysis of LOXL1 SNPs in POAG in the Hong Kong cohort.


Haplotype
rs1048661
rs3825942
rs2165241 		Haplotype frequency HS test (df=1)
p value		 SVH test
p value		 Odds ratio
(95% CI)
POAG Controls
H1 T G C 0.558 0.524 0.278 0.00336 1.15 (0.91–1.46)
H2 G G C 0.257 0.25 0.808 0.000419 1.03 (0.78–1.36)
H3 G A C 0.101 0.124 0.253 0.000756 0.80 (0.55–1.16)
H4 G G T 0.063 0.098 0.0249 0.00347 0.62 (0.40–0.97)
H5 T G T 0.021 0.004 0.00108 0.058 5.24 (1.17–23.54)

All haplotypes with frequency greater than 1% were shown in the table. HS test represented haplotype-specific test, and SVH test represents haplotype-based sole-variant test. The p values from the HS test were corrected by a permutation test by 1000 times of iterations. Omnibus χ2=18.16 (df=4); p=0.00115, Pperm=0.00399; n=293 case and n=250 control subjects.

Gong, Mol Vis 2008; 14:2381-2389. http://www.molvis.org/molvis/v14/a275

©2008 Molecular Vision http://www.molvis.org/molvis/

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