Figure 2. Splicing ratio of U12.
Splicing ratio of U12 containing intron
STK11 RNA in cell lines
were derived from control and splicing-factor mutated cell lines. Group
1 represents controls, group 2 represents PRPF31 carriers, group 3
represents PRPF31 severe, and group 4 represents PRPF8 cell lines. The
splicing ratios were obtained as described in the Methods section.
Means from four to six repeat experiments are shown ±SEM. For
individual cell line characteristics see
Table 1.