Figure 2. Effects of exogenous EGF, TGF-β1, or TGF-β2 on the spreading of the corneal endothelium in organ culture. Exogenous EGF promoted endothelium spreading. While adding exogenous TGF-β1 (A) or TGF-β2 (B) to the medium exhibited no effect on endothelium sheet elongation, it counteracted the promotion of endothelial sheet elongation by exogenous EGF.