Table 5 of Chowers, Mol Vis 2008; 14:2263-2271.

Table 5. Correlation among demographic and phenotypic characteristics of NVAMD and genotyping for HTRA1 (rs11200638)


HTRA1 (rs11200638) genotype
AA GA GG p
Gender (female/male) 14/10 25/25 29/40 0.35
Lesion type* (classic/occult) 7/17 22/28 26/43 0.46
Family History of AMD (yes/no) # 5/14 9/31 5/53 0.08
Age (mean ± SD, in years) 75.6±7 79.2±8.5 79.5±7.8 0.1
Smoking (yes/no) # 11/12 22/26 33/34 0.93
Initial VA (mean ± SD, logMAR) 1.1±0.8 0.928±0.7 1.1±0.8 0.38
Lesion size (mean ± SD, in µm) 4250±1261 3696±1290 3603±1261 0.17
Number of PDT sessions 2.5±1.9 2.4±1.8 2.2±1.9 0.78
Final VA (mean ± SD, logMAR) 1.6±0.84 1.5±0.84 1.36±0.94 0.45

The asterisk indicates classic lesions included predominantly classic and pure classic lesions. Occult lesions included minimally classic and occult lesions. Analysis according to four lesion types showed similar results. # Reliable information on family history was obtained from 117 out of the 143 participants included in this analysis, and smoking history was obtained from 138 of the 143 study participants.

Chowers, Mol Vis 2008; 14:2263-2271. http://www.molvis.org/molvis/v14/a262

©2008 Molecular Vision http://www.molvis.org/molvis/

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