Table 4 of Sun, Mol Vis 2008; 14:2237-2262.

Table 4. Ion transporters and channels expressed in vivo, but not detected in culture

Apical membrane Basal membrane Unknown polarity
Like Na+, K+, 2Cl- cotransporter (splice isoform A) Like Na+ conductance (voltage-gated, type 8) ATP2B1, Ca2+-ATPase
*KCNJ3, K+-inwardly rectifying channel L-type Ca2+ Channel NDCBE1, Na+-driven Cl−HCO3 exchanger
*KCNJ5, K+-inwardly rectifying channel CACNA1B, L-type Ca2+ Channel KCND2, K+-voltage-gated channel
KCNA4, K+-voltage-gated channel CACNA1C, L-type Ca2+ Channel TASK2, volume-sensitive K+-channel
KCNC1, K+-voltage-gated channel CACNB4, Ca2+ Channel KCNC1, K+-voltage-gated channel
SLC24A2, Na+/K+/Ca2+ exchanger
*TALK-1, K+- channel


SLC16A5, moncarboxylic transporter

For every cohort of genes described in this study, there were examples of genes that were expressed in vivo but not in culture. By far, ion transporters where the cohort that had the highest percentage of genes that cultured cells failed to express. Strikingly, most of these were potassium and calcium channels. The asterisk represents undetected in E14 cultures only.

Sun, Mol Vis 2008; 14:2237-2262. http://www.molvis.org/molvis/v14/a261

©2008 Molecular Vision http://www.molvis.org/molvis/

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