Molecular Vision: Kagemann, Mol Vis 2008; 14:2157-2170. Table 1

Table 1. Comparison of optical and histological structural measurements.

Hours post fertilization	SD-OCT retina (μm)	Histology retina (μm)	p
Mean	85.81±27.18	66.06±19.17	<0.0001
24	51.78±8.74	38.95±2.45	0.0055
48	73.30±5.64	50.23±2.69	ns
72	108.86±8.07	79.26±9.70	ns
120	114.23±7.78	84.91±8.00*	0.0015

Measurements of retinal thickness (mean±SD) were obtained from SD-OCT and histological sections and compared using paired Student’s t-test. Significant values are given in bold. To account for 5 comparisons, Bonferroni’s correction was used to require an adjusted p value of 0.01 for differences to be considered statistically significant. Measurements of retinal thickness obtained from SD-OCT images in vivo were consistently thicker than those obtained from histological sections in vitro. The abbreviation “ns” stands for nonsignificant. The asterisk indicates that histological retinal sections at 120 hpf may have experienced some flattening.