Figure 5. Profile of glycated human lens crystallins for all age groups in peripheral circulation. A: Profile of HMW+α-glycated crystallins in peripheral circulation during aging with respect to cataractogenesis as determined by non-competitive ELISA using polyclonal antibodies raised against human total lens proteins. Values are mean±SD at every given time point (n=5). The asterisk indicates that p<0.05, and the double asterisk indicates that p<0.001. N-apparently normal subjects; P-cataract patients. B: Profile of β-glycated crystallins in peripheral circulation during aging with respect to cataractogenesis as determined by non-competitive ELISA using polyclonal antibodies raised against human total lens proteins. Values are mean±SD at every given time point (n=5). The asterisk indicates that p<0.05, and the double asterisk indicates that p<0.001. N-apparently normal subjects; P-cataract patients. C: Profile of γ-glycated crystallins in peripheral circulation during aging with respect to cataractogenesis as determined by non-competitive ELISA using polyclonal antibodies raised against human total lens proteins. Values are mean±SD at every given time point (n=5). The asterisk indicates that p<0.05, and the double asterisk indicates that p<0.001. N-apparently normal subjects; P-cataract patients.