Table 3 of Shiels, Mol Vis 2008; 14:2042-2055.

Table 3. Two-Point LOD scores (Z) for linkage between the cataract locus in family Mu and markers on chromosome 1p.


Marker		 Distance from 1p-tel Z at θ= ZMax θMax
cM Mb 0.00 0.05 0.10 0.20 0.30 0.40
D1S2795 14.20 5.50 -0.47 2.24 2.24 1.88 1.33 0.66 2.27 0.07
D1S214 16.40 6.88 -0.44 2.27 2.27 1.91 1.35 0.67 2.30 0.08
rs707455   7.75 -3.70 -0.64 -0.37 -0.15 -0.05 -0.01 0.00 0.05
D1S2736 22.90 10.54 2.62 2.38 2.14 1.62 1.05 0.47 2.62 0.00
D1S489 32.30 11.97 1.54 1.41 1.28 1.01 0.71 0.38 1.54 0.00
D1S507 36.20 14.90 2.61 2.38 2.13 1.60 1.03 0.45 2.61 0.00
D1S2672 36.20 15.15 3.56 3.25 2.93 2.25 1.51 0.71 3.56 0.00
D1S436 39.90 15.74 2.84 2.59 2.32 1.76 1.15 0.52 2.84 0.00
D1S2697 39.90 16.29 2.92 2.66 2.39 1.82 1.20 0.55 2.92 0.00
EPHA2 c.2842G>T   16.32–16.36 3.61 3.30 2.98 2.28 1.52 0.72 3.61 0.00
D1S1592   17.94 1.26 1.16 1.05 0.83 0.59 0.32 1.26 0.00
rs477558   18.09 -4.43 -0.57 -0.33 -0.14 -0.06 -0.02 0.00 0.50
D1S2644 46.20 18.90 -∞ -0.38 -0.15 0.03 0.07 0.06 0.07 0.32

Z values for markers on 1p listed in genetic and physical distances measured in cM and Mb, respectively, from the telomere (1p-tel). The maximum Z values (Zmax) occurred at marker D1S2672, and at the c.2842G>T transversion in exon-17 of EPHA2. θ=recombination fraction.

Shiels, Mol Vis 2008; 14:2042-2055. http://www.molvis.org/molvis/v14/a241

©2008 Molecular Vision http://www.molvis.org/molvis/

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