Figure 1. Corneal endothelial photographs. A: Typical corneal endothelial photograph with alizarin red staining from a C57BL/6 wild type mouse at a young age. A=mean cell area, HSF=hexagon shape factor, quantifying the deviation from the ideal hexagonal cell shape; DE=degree of cell elongation; P=mean cell perimeter. B: SOD-3 null mouse, young age. The cells are enlarged, compared to the wildtype control. C: SOD-1/3 null mouse, young age. The cells are enlarged, compared to the wildtype control. D: SOD-1 null mouse, young age. E: Wild type mouse, old age. F: SOD-3 null mouse, old age. The cells are enlarged, compared to the wildtype control. G: SOD-1/3 null mouse, old age. Note that the cells are enlarged and show increased pleomorphism and polymegethism, compared to the wildtype control. H: SOD-1 null mouse, old age.