Figure 4. DNA sequence chromatograms of PEO1
for unaffected and affected members in the family. A single transition
was observed at position 1423 (G>A) of PEO1, causing a
substitution of Ala to Thr at codon 475 (A475T). A table of
phylogenetic conservation is also shown. Hs, Homo sapiens;
MaMu, Macaca Mutallata; Mm, Mus musculus; Cf, Canis
familiaris; Eq, Equus Caballus; Xl, Xenopus laevis,
Dm, Drosophila melanogaster.