Molecular Vision: Natoli, Mol Vis 2008; 14:1983-1994. Table 3

Table 3. Numbers of genes changing expression with hyperoxia.

	Time in hyperoxia
	3 days	7 days	14 days
Increased expression	509	967	933
Decreased expression	668	1426	2169
Total genes changing expression	1177	2393	3102
ANOVA	18	19	95
Retinal Disease Genes	0	0	15
GO: Response to stress	58	108	196
GO: Apoptosis-related	45	81	101

The number of genes regulated by hyperoxia, over a 14 day exposure, with a change of ±2 fold or greater is shown. The data were further analyzed and divided into catagories based on several criteria, including gene increases (first row), decreases (second row), total number of gene changes (third row), number of genes with a p<0.05 (ANOVA; fourth row) and genes associated with human retinal diseases (fifth row). Using Gene Ontology (GO), those genes associated with stress (sixth row) and apoptotic cell death (seventh row) were also determined.