Figure 4. Dose-dependent inhibition of
retinal neovascularization by pSilencersiVEGF Administration
of pSilencersiVEGF at doses 1–1000 ng to hypoxic mice
resulted in a dose-dependent inhibition of retinal neovascularization
as measured by counting the number of endothelial cell nuclei per
section, with a maximum inhibitory effect of 50% at the 1000 ng dose.
Asterisk (*) indicates p<0.05 compared to the control eye.