Figure 3. Multiple-sequence alignment and
DNA sequence chromatograms of BFSP2. A: The
multiple-sequence alignment of BFSP2 from primates, rodents, cattle,
and zebrafish to humans (Homo sapiens) is shown. The Arg339
residue is located within a highly conserved region. B: DNA
sequence chromatograms of the P.R339H mutation in BFSP2 are
shown. The G→A transversion at position 1091 resulted in the P.R339H
mutation.