Table 3 of Tanito, Mol Vis 2008; 14:1898-1905.

Table 3. Odds ratios and p values for allelic and genotypic frequencies of rs1048661, rs3825942, and rs2165241 in comparison between cases (EX, EG, and EX+EG) and controls (CT, PG, NG, and PG+NG).


Parameter		 EX EG EX+EG
Versus CT Versus PG Versus NG Versus PG+NG Versus CT Versus PG Versus NG Versus PG+NG Versus CT Versus PG Versus NG Versus PG+NG
rs1048661
Allele
p value 1.69x 10–23 3.23x 10–13 2.55x 10–16 4.08x 10–19 5.65x 10–33 1.92x 10–17 1.32x 10–21 4.71x 10–26 3.00x 10–45 2.61x 10–20 4.40x 10–26 1.18x 10–33
OR 19.71 16.67 18.39 17.64 28.23 23.88 26.35 25.27 23.97 20.27 22.37 21.45
95% CI 8.90–43.67 6.91–40.22 7.84–43.14 7.80–39.88 12.83–62.14 9.96–57.27 11.31–61.41 11.25–56.76 13.40–42.87 10.14–40.56 11.60–43.16 11.67–39.43
Genotype
p value 4.11x 10–25 1.16x 10–11 1.91x 10–17 2.31x 10–19 4.80x 10–32 2.12x 10–14 6.50x 10–21 3.42x 10–24 3.78x 10–43 1.04x 10–16 2.74x 10–25 3.57x 10–31
rs3825942
Allele
p value 1.77x 10–8 2.10x 10–33 2.10x 10–33 2.10x 10–33 2.42x 10–22 6.48x 10–8 4.72x 10–9 1.23x 10–10 3.98x 10–16 8.68x 10–10 1.47x 10–11 1.84x 10–14
OR 28.21 29.25 29.93 29.64 39.78 41.25 42.21 41.8 34 35.25 36.07 35.72
95% CI 3.86–205.97 3.79–225.66 3.96–226.36 4.01–219.07 5.46–289–78 5.36–317.49 5.59–318.47 5.67–308.20 8.23–140.45 7.91–157.16 8.31–156.49 8.50–150.11
Genotype
p value 2.10x 10–33 2.10x 10–33 2.10x 10–33 2.10x 10–33 3.53x 10–11 7.19x 10–8 2.88x 10–9 1.11x 10–10 6.37x 10–16 1.20x 10–9 1.00x 10–11 1.17x 10–14
rs2165241
Allele
p value 4.79x 10–5 0.3051 1.03x 10–33 1.20x 10–3 7.87x 10–7 0.1022 4.87x 10–6 8.28x 10–5 1.08x 10–9 0.0729 1.52x 10–7 3.02x 10–6
OR 16.59 4.56 18.87 12.39 23.4 6.43 26.61 17.47 20 5.49 22.74 14.93
95% CI 2.25–122.20 0.47–44.63 2.45–145.49 1.63–94.08 3.18–171.92 0.66–62.81 3.46–204.70 2.31–132.36 4.78–83.62 0.90–33.46 5.11–101.30 3.42–65.14
Genotype
p value 1.95x 10–4 0.3 1.59x 10–4 2.82x 10–3 5.14x 10–6 0.1004 7.16x 10–6 1.23x 10–4 1.07x 10–8 0.0715 2.79x 10–7 4.71x 10–6

OR, odds ratio; CI, confidence interval; NA, not applicable; EX, exfoliation syndrome; EG, exfoliation glaucoma; PG, primary open-angle glaucoma aged 70 years or older; NG, normal tension glaucoma aged 70 years or older; and CT, cataract aged 70 years or older. p values were obtained by Fisher's exact probability test.

Tanito, Mol Vis 2008; 14:1898-1905. http://www.molvis.org/molvis/v14/a225

©2008 Molecular Vision http://www.molvis.org/molvis/

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