Table 1 of Chowers,
Mol Vis 2008; 14:1829-1834. Table 1 of Chowers,
Mol Vis 2008; 14:1829-1834.
Table 1. The frequency of alleles and genotypes of complement factor H rs1061170 SNP in Israeli NVAMD patients and unaffected controls
| Population | Age-related macular degeneration | Unaffected | p value | OR (95% CI) |
|---|---|---|---|---|
| By allele (T/C) | ||||
| Entire population | 237/243 (49.4%/50.6%) | 152/84 (64.4%/35.6%) | 0.0002 | 1.9 (1.3–2.6) |
| Ashkenazi Jews | 147/161 (47.7%/52.3%) | 87/47 (64.9%/35.1%) | 0.0009 | 2 (1.3–3.1) |
| Sephardic Jews | 74/72 (50.6%/49.4%) | 51/29 (63.7%/36.3%) | 0.07 | 1.7 (1–3) |
| By genotype | ||||
| Entire Population | ||||
| TT | 55 (22.9%) | 49 (41.5%) | 0.00047 | |
| TC | 127 (52.9%) | 54 (45.8%) | 2.1(1.3–3.4) | |
| CC | 58 (24.2%) | 15 (12.7%) | 3.4 (1.7–6.8) | |
| Ashkenazi Jews | ||||
| TT | 33 (21.4%) | 27 (40.3%) | 0.003 | |
| TC | 81 (52.6%) | 33 (49.3%) | 1.9 (1–3.8) | |
| CC | 40 (26%) | 7 (10.4%) | 13.9 (3.1–62.5) | |
| Sephardic Jews | ||||
| TT | 18 (24.7%) | 17 (42.5%) | 0.19 | |
| TC | 38 (52%) | 17 (42.5%) | 1.8 (0.7–1.9) | |
| CC | 17 (23.3%) | 6 (15%) | 2.8 (0.9–9.5) | |