Table 4 of Yuan, Mol
Vis 2008; 14:1792-1798.
Table 4. Upregulated pathways in Candida albicans keratitis compared with mock-infected controls.
Signaling pathway |
Log (p value) |
Number of genes involved |
Number upregulated genes |
Ratio |
|---|---|---|---|---|
| Leukocyte extravasation | 16 | 191 | 44 | 0.23 |
| NF-κβ | 15.5 | 141 | 38 | 0.27 |
| Interleukin 10 | 13.2 | 68 | 23 | 0.34 |
| Interleukin 6 | 12.5 | 90 | 27 | 0.3 |
| Acute-phase response | 11.3 | 171 | 36 | 0.21 |
| B cell receptor | 6.7 | 144 | 26 | 0.18 |
| Toll-like receptor | 6.6 | 50 | 14 | 0.28 |
| Integrin | 6.1 | 188 | 30 | 0.16 |
| Natural killer cell | 6 | 112 | 19 | 0.17 |
| Granulocyte-macrophage colony-stimulating factor | 5.8 | 63 | 15 | 0.24 |
| Transforming growth factor beta | 4.9 | 84 | 16 | 0.19 |
| Chemokine | 4.7 | 75 | 15 | 0.2 |
| Interleukin 2 | 4.5 | 52 | 12 | 0.23 |
| Insulin-like growth factor 1 | 3.8 | 94 | 15 | 0.16 |
| T cell receptor | 3.5 | 100 | 15 | 0.15 |
| Epidermal growth factor | 3 | 47 | 9 | 0.19 |
| Vascular endothelial growth factor | 3 | 93 | 13 | 0.14 |
| Interleukin 4 | 3 | 69 | 11 | 0.16 |
| JAK/STAT | 2.6 | 112 | 19 | 0.17 |
| Apoptosis | 2.5 | 62 | 8 | 0.13 |