Figure 2. Differential upregulation and down-regulation of corneal genes. Microarray results compare gene expression levels in mouse corneas from Candida albicans-infected compared to corneas from mock-infected controls. The results were assigned to general categories based upon the known functions of the gene products. The number of genes expressing a twofold or greater significant difference (p≤0.05) is plotted for the listed categories. Red bars represent the number of genes significantly down-regulated, and black bars represent the number of genes significantly upregulated.