Figure 6 of Dibas, Mol Vis 2008; 14:1770-1783.


Figure 6. A single intravitreous ET-1 injection and elevation of intraocular pressure decreased thy-1 protein levels in rat retinas. Thy-1 expressed by retinal ganglion cells is widely used as marker for RGC early stress and was shown to be reduced following ET injection and elevation of IOP by ~ 25%. Data are expressed as a ratio of the control value and each column represents mean±SEM. Densitometric quantification is shown in C and D. The asterisk denotes statistical significance of thy-1 in ET-injected retinas versus control (p<0.05) and the double asterisk denotes statistical significance of thy-1 in elevated IOP-retinas versus control (p<0.05) as determined by one-way ANOVA and Tukey multiple comparison test. Abbreviations: control eye (C), ET-injected eye (E), and elevated IOP (T).