Table 4 of Burdon, Mol Vis 2008; 14:1727-1736.

Table 4. Power calculations.

Genotypic
relative
risk Aa/AA		 Linkage
disequilibrium
D’		 Risk and
 marker allele
frequency		 Power
at α=0.05
1.5/2.0 0.8 0.2 0.4


0.3 0.44


0.4 0.44
1.5/2.0 1 0.2 0.57


0.3 0.62


0.4 0.61
2.0/3.0 0.8 0.2 0.83


0.3 0.84


0.4 0.8
2.0/3.0 1 0.2 0.96


0.3 0.96


0.4 0.94

Power in this population-based study to detect a significant genetic association for pseudoexfoliation syndrome at the α=0.05 level for different degrees of linkage disequilibrium and allele frequency. Aa=heterozygote, AA=high risk homozygote.

Burdon, Mol Vis 2008; 14:1727-1736. http://www.molvis.org/molvis/v14/a205

©2008 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535