Table 3 of Burdon, Mol Vis 2008; 14:1727-1736.

Table 3. Haplotype association between variants across the CLU gene and pseudoexfoliation syndrome.


SNPs Frequency p values
Hap 1 2 3 4 5 6 7 8 9 Controls Cases Additive Dominant
1 T G C C T G T C A 0.24 0.28 0.23 0.12
2 G G C C T A C C A 0.17 0.15 0.347 0.246
3 T A T C C G C G G 0.09 0.08 0.931 0.64
4 T G C C T G T C G 0.07 0.11 0.008 0.005
5 T A T C T G C G G 0.04 0.05 0.444 0.42
6 G G C C T A C C G 0.04 0.02 0.448 0.453
7 T G C C T G C C A 0.03 0.05 0.488 0.458
8 G G C G T A C C G 0.03 0.03 0.923 0.971
9 T G C C T G C G G 0.03 0.01 0.157 0.156
10 T G T C T G T C G 0.02 0.04 0.22 0.22

Haplotypes (Hap) with frequency greater than 2% in the total cohort (n=2508) are shown with the p values for association under additive and dominant models. The nominally associated haplotype 4 is highlighted in bold. SNPs forming the haplotype are numbered as in Table 1.

Burdon, Mol Vis 2008; 14:1727-1736. http://www.molvis.org/molvis/v14/a205

©2008 Molecular Vision http://www.molvis.org/molvis/

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