Table 4 of Li, Mol Vis 2008; 14:1698-1704.

Table 4. Relationship between EDN1genotype, age of diabetes mellitus onset, and hypertension

Factors Lys/Lys Lys/Asn Asn/Asn p value
Number of patients 216 108 19
Age of diabetes mellitus onset 53.1+/-11.1 53.0+/-11.6 59.0+/-11.6 0.02
Hypertensive 143 (61.9%) 74 (32.0%) 14 (6.0%) 0.79
Nonhypertensive 73 (65.2%) 34 (30.4%) 5 (4.5%)

The onset age of diabetes mellitus (DM) and hypertension frequency were compared among different EDN1 genotypes in all diabetic patients. The age of DM onset of patients with the Asn/Asn genotype was about six years later than patients with other genotypes (p=0.02) and Lys198Asn genotype distributions were not different between hypertensive and nonhypertensive subjects (p=0.79).

Li, Mol Vis 2008; 14:1698-1704. http://www.molvis.org/molvis/v14/a201

©2008 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535