Table 2 of Li, Mol
Vis 2008; 14:1698-1704. Table 2 of Li, Mol
Vis 2008; 14:1698-1704.
Table 2. Genotype and allele frequencies in groups with and without retinopathy
| Polymorphism | Genotype distribution (%) | Allele distribution (%) | ||||||
|---|---|---|---|---|---|---|---|---|
DM (n=127) |
DR subtypes | DM (n=254) |
DR subtypes | |||||
| NPDR (n=144) | PDR (n=72) | NPDR (n=288) | PDR (n=144) | |||||
| EDN1 Lys198Asn | Lys/Lys | 66 (52.0) | 109 (75.7) | 41 (56.9) | Lys | 179 (70.5) | 249 (86.5) | 112 (77.8) |
| Lys/Asn | 47 (37.0) | 31 (21.5) | 30 (41.7) | Asn | 75 (29.5) | 39 (13.5) | 32 (22.2) | |
| Asn/Asn | 14 (11.0) | 4 (2.8) | 1 (1.4) | |||||
| p value | all DR versus DM: 0.0002 | all DR versus DM: 0.007 | ||||||
| NPDR versus DM: 0.0001 | NPDR versus DM: 0.00005 | |||||||
| PDR versus NPDR: 0.008 | ||||||||
| eNOS Glu298Asp | Glu/Glu | 98 (77.2) | 110 (76.9) | 55 (76.4) | Glu | 224 (88.2) | 249 (87.1) | 127 (88.2) |
| Glu/Asp | 28 (22.0) | 29 (20.3) | 17 (23.6) | Asp | 30 (11.8) | 39 (12.9) | 17 (11.8) | |
| Asp/Asp | 1 (0.8) | 4 (2.8) | 0 (0) | |||||
| ITGA2 BgI II | BgI II (-/-) | 65 (51.2) | 76 (52.8) | 33 (45.8) | - | 184 (72.4) | 211(73.3) | 100 (69.4) |
| BgI II (-/+) | 54 (42.5) | 59 (41.0) | 34 (47.2) | + | 70 (27.6) | 77 (26.7) | 44 (30.6) | |
| BgI II (+/+) | 8 (6.3) | 9 (6.3) | 5 (6.9 ) | |||||
| LTA IVS1-80C>A | CC | 64 (50.4) | 76 (53.1) | 31 (43.7) | C | 174 (68.5) | 210 (73.4) | 94 (66.2) |
| CA | 46 (36.2) | 58 (40.6) | 32 (45.1) | A | 80 (31.5) | 76 (26.6) | 48 (33.8) | |
| AA | 17 (13.4) | 9 (6.3) | 8 (11.3) | |||||
| LTA IVS1-252A>G | AA | 31 (24.4) | 30 (20.8) | 19 (26.4) | A | 127 (50.0) | 134 (46.5) | 71 (49.3) |
| GA | 65 (51.2) | 74 (51.4) | 33 (45.8) | G | 127 (50.0) | 154 (53.2) | 73 (50.7) | |
| GG | 31 (24.4) | 40 (27.8) | 20 (27.8) | |||||
| LTA IVS1-206G>C | GG | 63 (49.6) | 76 (52.8) | 34 (47.2) | G | 173 (68.1) | 210 (72.9) | 101 (70.1) |
| GC | 47 (37.0) | 58 (40.3) | 33 (45.8) | C | 81 (31.9) | 78 (27.1) | 43 (29.9) | |
| CC | 17(13.4) | 10 (6.9) | 5 (6.9) | |||||