Table 3 of Demos, Mol Vis 2008; 14:1639-1649.

Table 3. Enzyme activity for Pla2g7 in retinal degeneration

Genotype
treatment
Control
Experimental
p-value
rd1 0.2753±0.01 0.1953±0.006 <0.01
rd2 0.0805±0.0035 0.027±0.0.0032 <0.001
light damage 0.123±0.015 0.059±0.0012 <0.001

Quantification of specific activity of Pla2g7 [μmol/minute/mg of protein] in retina extracts collected from P10 rd1, P21 rd2 mice, and 3-month old BALB/c mice after 24 h of light damage (column 2), together with their age-matched controls (column 3). Cytosolic levels of Pla2g7 were significantly reduced (column 4) in all three models of photoreceptor degeneration. Data is expressed as mean±SEM for 3-5 samples per condition.

Demos, Mol Vis 2008; 14:1639-1649. http://www.molvis.org/molvis/v14/a194

©2008 Molecular Vision http://www.molvis.org/molvis/

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