Figure 2. Pedigree of the family with X-linked juvenile retinoschisis. Black boxes represent affected males, while circles with a black dot in the center represent carrier females by sequence analysis. The circle with an open dot represents a female that is expected to be an obligate carrier female. Red numbers mark family members who underwent complete clinical and molecular genetic examinations. Red arrow points to the proband. Slashed boxes are deceased family members. Patients III/2 and III/3 are fraternal twins.