Figure 2. Haplotype analysis of the GZ.1 pedigree using microsatellite markers encompassing MYOC on the long arm of chromosome 1. MYOC resides between markers D1S196 and D1S2818. Square cells refer to males and circle cells refer to females; Filled cells are JOAG; diagonal line, deceased; and arrow, proband. The analysis was performed in 24 informative family members including 16 affected and 8 unaffected individuals. Segregating haplotypes are shown in the rectangles.