Figure 1. Pedigree structure of the
Chinese family with 19 affected subjects in 5 generations. Squares
indicate male subjects; circles, female subjects; solid symbols,
affected family members with JOAG; unfilled symbols, unaffected family
members; diagonal line, deceased individual. Arrow indicates the
proband (III:7). According to the distribution of the affected members,
the heredity of the GZ.1pedigree is autosomal dominant.
![](images/mv-v14-1533-f1.jpg)