Table 8 of Francis, Mol Vis 2008; 14:1395-1400.

Table 8. Joint analyses of the CFH SNP and 10q26 haplotypes

rs10490924 +
rs11200638		 rs1061170 rs10490924 +
rs11200638 risk
(adjusted for rs1061170)

TT TC CC
GG/GG 1 2.09 4.48 1
Non GG/GG 5.44 14.4 26.86 6.49 (95% CI: 4.01, 10.50)
rs1061170 risk (adjusted for rs10490924 + rs11200638) 1 2.34 (95% CI: 1.34, 4.08) 4.90 (95% CI: 2.40, 10.00)

The haplotype information for 10q26 gene is estimated using software PHASE. By treating the haplotype GG (formed by high risk alleles G and G at rs10490924 and rs11200638) as a new “allele”, we studied the joint and main effects of CFH SNP-10q26 haplotypes as in Table 3. Here a recessive mode of inheritance for 10q26 gene is assumed so that the gentotypes are classified to GG/GG and non GG/GG.

Francis, Mol Vis 2008; 14:1395-1400. http://www.molvis.org/molvis/v14/a168

©2008 Molecular Vision http://www.molvis.org/molvis/

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