Table 3 of Julien, Mol Vis 2008; 14:1358-1372.

Table 3. Similitude of our experimental rabbit CNV model with the features observed in patients suffering from wet AMD

-> Changes in the RPE (hypo- or hyperpigmentation)
-> Bruch’s membrane loss and infiltration of endothelial cells
-> Remodelling of extracellular matrix
-> Subretinal neovascularisation
-> Proliferation of endothelial cells and fibroblasts
-> Subretinal haemorrhage
-> Leakages
-> Thrombosis
-> Loss of photoreceptors
-> Retinal edema
-> Upregulation of bFGF and VEGF