Table 3 of Julien,
Mol Vis 2008; 14:1358-1372. Table 3 of Julien,
Mol Vis 2008; 14:1358-1372.
Table 3. Similitude of our experimental rabbit CNV model with the features observed in patients suffering from wet AMD
| -> Changes in the RPE (hypo- or hyperpigmentation) |
| -> Bruch’s membrane loss and infiltration of endothelial cells |
| -> Remodelling of extracellular matrix |
| -> Subretinal neovascularisation |
| -> Proliferation of endothelial cells and fibroblasts |
| -> Subretinal haemorrhage |
| -> Leakages |
| -> Thrombosis |
| -> Loss of photoreceptors |
| -> Retinal edema |
| -> Upregulation of bFGF and VEGF |