Figure 4 of Zenteno, Mol Vis 2008; 14:1353-1357.

Figure 4. WFS1 gene novel frameshift mutation in WS. Exon 8 sequence analysis revealed that a normal tract of 16 bp (boxed in A) is heterozygously deleted in DNA from an affected subject (case 1) (B). The deletion predicts the introduction of a premature stop signal 65 codons downstream residue 451 of Wolframin.