Table 2 of Mabuchi, Mol Vis 2008; 14:1303-1308.

Table 2. rs1048661 and rs3825942 compound genotypes in patients with primary open angle glaucoma and exfoliation syndrome and control subjects.

Genotype
rs1048661T/G/
rs3825942A/G
Control
(n=191)
POAG
(n=213)

p value*
XFS**
(n=89)

p value*
GG/AA 8 (4.2) 6 (2.8)
0 (0)
GG/AG 14 (7.3) 15 (7.0)
0 (0)
GG/GG 18 (9.4) 26 (12.2) 0.76 0 (0) < 0.0001
TG/AG 26 (13.6) 37 (17.4)
1 (1.1)
TG/GG 66 (34.6) 70 (32.9)
0 (0)
TT/GG 59 (30.9) 59 (27.7)
88 (98.9)

A significant difference in compound genotype frequencies was noted between XFS patients and control subjects. Data are given as numbers (percentage). The asterisk indicates that the χ2 test was done. The double asterisk indicates that 67 of 89 XFS patients had exfoliation glaucoma. POAG: primary open-angle glaucoma, XFS: exfoliation syndrome.

Mabuchi, Mol Vis 2008; 14:1303-1308. http://www.molvis.org/molvis/v14/a156

©2008 Molecular Vision http://www.molvis.org/molvis/

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