Table 1 of Mabuchi,
Mol Vis 2008; 14:1303-1308.
Table 1. Genotype and allele frequencies of rs1048661 and rs3825942 in patients with primary open angle glaucoma and exfoliation syndrome and control subjects.
SNP |
Genotype/Allele |
Control (n=191) |
POAG (n=213) |
p value* |
XFS** (n=89) |
p value* |
rs1048661 (Arg141Leu) |
Genotype | |||||
TT (Leu/Leu) | 59 (30.9) | 59 (27.7) | 88 (98.9) | |||
TG (Leu/Arg) | 92 (48.2) | 107 (50.2) | 0.78 | 1 (1.1) | <0.0001 | |
GG (Arg/Arg) | 40 (20.9) | 47 (22.1) | 0 (0) | |||
Allele | ||||||
T | 210 (55.0) | 225 (52.8) | 0.57 | 177 (99.4) | <0.0001 | |
G | 172 (45.0) | 201 (47.2) | 1 (0.6) | |||
rs3825942 (Gly1153Asp) |
Genotype | |||||
AA (Asp/Asp) | 8 (4.2) | 6 (2.8) | 0 (0) | |||
AG (Asp/Gly) | 40 (20.9) | 52 (24.4) | 0.57 | 1 (1.1) | <0.0001 | |
GG (Gly/Gly) | 143 (74.9) | 155 (72.8) | 88 (98.9) | |||
Allele | ||||||
A | 56 (14.7) | 64 (15.0) | 0.92 | 1 (0.6) | <0.0001 | |
G | 326 (85.3) | 362 (85.0) | 177 (99.4) |