Table 4 of Rao, Mol Vis 2008; 14:1254-1262.
Table 4 of Rao, Mol Vis 2008; 14:1254-1262.
Table 4. The estimated haplotype frequencies and their odds ratios based on two SNPs (rs1048661 and rs3825942) across different secondary glaucoma phenotypes in the present cohort and other populations.
| Populations, [n (cases, controls)] | Pheno-types | G-G haplotype | T-G haplotype | Reference | |||||||||
| % Cases | % Controls | OR (95%CI)* | p value | %Cases | %Controls | OR (95%CI)* | p value | ||||||
| Sweden [399,198] | XFG | 83.3 | 56.1 | 35.72# | 2.2x10−16 | 16.2 | 31.8 | 12.36# | 1.6x10−6 | [9] | |||
| Iceland [195,14474] | XFG | 81.4 | 49.8 | 18.94# | 3.3x10−12 | 17.3 | 34.9 | 5.74# | 0.0027 | [9] | |||
| USA [72,75] | XFS | 80.6 | 48 | 14.50 (3.27–64.35) | 2.7x10−5 | 18.1 | 40 | 3.90 (0.84–18.04) | 0.12 | [10] | |||
| American and European [566,658] | XFS | 80.2 | 50.3 | 4.00 (3.10–5.18) | 1.5x10−7 | 15.7 | 29.6 | 0.44 (0.33–0.59) | 9.0x10−9 | [13] | |||
| Germany and Italy [726,418] | XFS/XFG | 78.6 | 50.7 | 3.58 (2.98–4.32) | 5.2x10−43 | 17.9 | 34.6 | NA | NA | [14] | |||
| Europe [167,170] | XFG | 83.5 | 48.8 | 52.1 (13.85–195.6) | NA | 15.9 | 32.9 | 14.67 (3.81–56.2) | NA | [18] | |||
| India [52,97] | XFS/XFG | 64 | 37 | 5.74 (2.53–12.98) | 9.9x10−6 | 27 | 36 | 2.55 (1.07–6.05) | 0.129 | [15] | |||
| Australia [86,2422] | XFS | 74 | 51 | 2.71 (1.91–3.92) | 3.8x10−9 | 22 | 34 | 0.54 (0.36–0.78) | 7.8x10−4 | [17] | |||
| USA [78, 108] | PG/PDS | 52.9 | 55.3 | 1.08 (0.59–1.97) | 0.643 | 32.3 | 26.9 | 1.35 (0.70–2.60) | 0.266 | Present study | |||