Figure 2. Slit lamp photographs of the
affected family members with LCD I due to an R124C mutation in TGFBI.
A: The eye of proband in family A (IV-10) shows the typical
lattice lines of LCD I (white arrow). B and C: III-4 of
family A (B) and II-5 of family C (C) show diffuse
opacity occupying the central cornea with superimposed amorphous
deposits (yellow arrow), which is quite different from typical LCD I.
III-4 from family A also manifested thin branching refractive lines in
the anterior corneal stroma (white arrow). D: The eye of the
proband of family B (III-3) shows a diffuse opacity throughout the
cornea, and no lattice lines could be found. There is also neovascular
infiltration from the limbus of the cornea (black arrows).